Fulgorex provides a battery-swapping network for electric semi-trucks, allowing fleets to pay for energy as a service rather than building their own charging stations. This approach cuts refueling time from an hour to under two minutes, eliminating costly delays and making electric trucking cheaper to operate than diesel.
Izote Biosciences engineers microbes to consume a salt called perchlorate instead of oxygen during fermentation. This removes the need for expensive aeration equipment, lowering the cost and complexity of scaling up biomanufacturing.
Bioqore combines artificial intelligence with physical lab automation to speed up the manufacturing process for biological drugs. This prevents life-saving treatments from failing due to slow and expensive manufacturing bottlenecks, saving biotech companies years of time and millions of dollars.
iQ Sense is building an implantable optical biosensor that generates real-time molecular data for animal health. This platform shifts veterinary care from reactive snapshots to continuous, predictive tracking that improves treatment outcomes and adherence.
L2X Labs builds proprietary Extreme UV light sources that allow semiconductor manufacturers to inspect and measure next-generation chips at the nanometer scale. This technology provides the clean, high-brightness light needed to catch critical flaws and produce the advanced chips powering AI and modern computing.
Operon Technologies builds modular, software-defined power systems that replace traditional grid infrastructure for heavy industries. This allows data centers and manufacturing sites to bypass long utility backlogs and deploy grid-ready power in weeks instead of years.
Hyperscale provides on-demand metal manufacturing through a blue laser microwire 3D printing platform that produces critical, high-temperature metal parts. This technology restores domestic manufacturing capabilities and cuts production lead times from over a year to just a few days for the aerospace, defense, and energy sectors.
Intellis Sky builds drone-mounted radar systems that can see through clouds, smoke, and darkness to collect high-resolution aerial data at any time of day. This technology provides governments and businesses with instant, affordable, and continuous observation that traditional satellites and aircraft cannot match.
Modal Motors builds advanced electric propulsion systems that completely eliminate the need for rare-earth materials. This approach lowers production costs, improves motor performance, and secures a fully domestic supply chain independent of foreign markets.
Daedal Systems builds standardized measurement tools, known as plasma diagnostics, to provide independent validation of fusion energy results. By acting as a third-party referee, the company helps fusion startups prove their progress to investors and accelerates the development of clean energy.
ThermoCirca builds advanced battery backup units that use immersion cooling to handle the massive power surges required by modern AI data centers. This technology prevents grid failures and allows AI hardware to scale without being limited by power constraints.
Brightlight Photonics builds integrated, chip-scale Ti:sapphire laser modules that combine high performance with scalable manufacturing. This technology removes current bottlenecks in advanced systems by providing compact, high-power lasers for quantum sensing, precision timing, and aerospace.
Cascade uses real-time scanning and AI to predict dangerous geohazards like landslides and rockfalls for mines and railroads. This technology prevents billions of dollars in damage and saves workers' lives by giving operators early warnings about hidden risks.
Omnibio creates robotic control software by training biological brain cells in simulations and converting them into digital algorithms that run directly on robots. This allows industrial machines to handle new objects and recover from errors automatically, saving companies from expensive downtime and constant reprogramming.
Ci Labs builds foundation models for physical artificial intelligence that help robots reliably perform complex, contact-heavy tasks like grasping and assembly. This technology bridges the gap between lab research and real-world use, bringing scalable automation to industries ranging from electronics manufacturing to heavy machinery.
Ada Labs builds autonomous robots that scan greenhouse plants daily to create digital models for crop health and labor planning. This technology helps growers combat shrinking workforces and rising labor costs by turning field data into measurable yield improvements.
Skip Technology builds next-generation hydrogen-bromine flow batteries that provide safe, long-duration energy storage. This technology offers a fully domestic alternative to lithium-ion batteries, helping to meet the massive electricity demands of data centers and renewable energy grids without relying on foreign supply chains.
Volador Energy builds adaptable, modular battery energy storage systems that work with any battery chemistry to provide long-lasting, safe power. This approach solves major industry problems like short battery lifespans and dangerous fire hazards while lowering the total cost of ownership.
Aqua-Cell Energy builds large-scale, long-duration flow batteries using cheap salt-water and standard parts from the water treatment industry. This approach provides a safe and scalable way to store renewable energy and strengthen the power grid without relying on expensive critical minerals.
Buzz Biolabs genetically engineers the Black Soldier Fly to act as a living factory that produces drugs, enzymes, and other biological products. This approach replaces expensive steel bioreactors with a highly scalable system that drastically cuts the cost and time required to manufacture medicines.
Precision Discovery Systems builds a nanoliter liquid handling machine that verifies fluid transfers in real time for drug discovery labs. This prevents silent errors from ruining automated experiments and ensures that AI-generated hypotheses are tested with accurate physical data.
KiraGen Bio engineers off-the-shelf immune cells with multiple genetic edits designed to resist the suppressive environment of solid tumors. This approach prevents the immune cells from shutting down, creating long-lasting and affordable treatments for difficult cancers like glioblastoma.
Nonfiction Laboratories engineers remote-controlled drugs that can be turned on or off in specific parts of the body using magnetic fields. This allows doctors to safely deliver powerful treatments that were previously abandoned because they caused fatal side effects.
Rosalind Dx develops a rapid, low-cost prenatal testing kit that uses standard PCR technology to detect genetic conditions like Down Syndrome from a blood sample. This allows everyday diagnostic labs to offer affordable screening, expanding access to the 97% of pregnant women worldwide who currently cannot get tested.
Future Intelligence Labs is an AI-native chip design house that uses autonomous agents to deliver production-ready silicon without the need for expensive human design teams. This approach eliminates long hiring cycles and prevents costly design failures that can waste hundreds of millions of dollars.
Kenyi Technologies designs ARM-based edge server processors that combine a CPU and a custom data processing unit into a single chip. This allows telecom operators to run advanced AI and 6G applications directly at cell sites while staying within strict power and budget limits.
icspi builds extremely small atomic force microscopes that run in parallel to inspect semiconductor wafers at the atomic level. This technology allows chipmakers to catch tiny defects and improve manufacturing yields at speeds that were previously impossible with traditional tools.
Visibl Semiconductors is an AI-powered chip design service that helps hardware companies create custom silicon faster and cheaper. This approach allows businesses to get specialized chips without the massive expense of building their own internal engineering teams.
Intrlace builds a monolithic optical packaging platform that replaces expensive manual assembly with a single piece of hardware for data center interconnects. This technology drastically cuts networking costs, making it easier and cheaper for data centers to scale their AI computing power.
Carbon Infuse turns industrial waste and carbon dioxide emissions into eco-friendly materials that can replace traditional cement. This solves a massive shortage of building materials while making concrete stronger, cheaper, and significantly better for the environment.
Lotus Matter develops engineered microparticles that capture carbon emissions directly from cement production plants. This technology provides a low-cost, highly efficient way to drastically reduce the massive carbon footprint of the cement industry without requiring expensive facility rebuilds.
Velontra builds low-cost jet engines for drones and aircraft using rapid aerospace manufacturing methods. This technology provides affordable propulsion for the next generation of unmanned defense vehicles and paves the way for hypersonic flight and runway-to-orbit space access.
DAURALIS builds physical anti-drone defense systems specifically designed to protect data centers and civilian critical infrastructure. This technology fills a major security gap by stopping escalating drone threats before they reach the property line, ensuring essential facilities remain safe without violating civilian airspace rules.
KVector builds a new type of dynamic antenna that steers radio beams electronically without the heavy, power-hungry parts found in traditional systems. This approach makes high-frequency communications and radar smaller, cheaper, and more energy-efficient, unlocking better performance for satellites and military networks.
Outcome Group builds high-performance, AI-ready drone platforms that are manufactured entirely in the United States. This provides a secure, domestic supply chain for mission-critical aerial operations and solves major production gaps in the defense and commercial markets by avoiding reliance on foreign manufacturing.
INXTECH builds zero-emission autonomous underwater vehicles and AI software to collect high-resolution subsea data. This technology replaces expensive, carbon-heavy manned vessels to make ocean surveying cheaper and more efficient for the offshore energy and defense industries.
Larmor mmWave Systems builds fully integrated, high-power microwave sources called gyrotrons to provide the essential heating and control systems needed for commercial nuclear fusion and deep geothermal drilling. This technology solves a major bottleneck for next-generation energy industries by replacing slow, custom-built hardware with standardized, ready-to-use systems.
P-Logic Innovations builds smart safety hardware that processes sights, sounds, and environmental hazards directly on the device without needing the cloud. This allows emergency response and security companies to offer faster, more reliable protection that works even during power and internet outages.
ZdefLabs replaces manual, paper-based calibration for lab instruments with a sensor-based system that provides precise, traceable data. This technology gives engineers exact control over liquid transfers, preventing costly errors, saving expensive materials, and reducing equipment downtime.
Atomic Factories provides instant-quote metal 3D printing services using their own custom-built printers to make metal parts cheaper and faster than traditional machining. This approach lowers the barrier to fast metal manufacturing and helps bring industrial production back to the United States.
YPlasma builds solid-state plasma actuators that use electric fields to create a silent breeze of charged particles, replacing traditional fans with vibration-free cooling technology. This allows high-performance electronics, data centers, and electric vehicles to overcome thermal limits without adding bulky or noisy moving parts.
Magmatic Bio uses an AI-powered bioengineering platform to design synthetic proteins that bind and separate critical metals with atomic precision. This technology allows the mining and recycling industries to extract valuable resources from low-concentration streams where traditional chemical processing fails, creating a more sustainable supply chain for essential minerals like lithium and manganese.
Materis Labs provides an AI-powered platform that predicts how different materials will interact and potentially fail when combined in manufacturing. This prevents billion-dollar delays in semiconductor and advanced hardware production by catching integration issues before expensive commitments are made.
TioTech produces a specialized battery material called TitanB that creates ultra-safe, fast-charging lithium-ion batteries for heavy industries. This technology provides extreme durability and reliable power for demanding applications like defense, maritime, and logistics where standard batteries struggle with safety, cold weather, and short lifespans.
Vessl Prosthetics creates an automatically adjusting prosthetic socket that uses the energy from walking to maintain a perfect fit as a patient's limb changes size throughout the day. This eliminates the pain and wounds caused by poorly fitting prosthetics while saving clinics time and money on constant readjustments.
River creates assistive communication tools that help people with speech impairments talk without needing to type. This technology gives millions of people with conditions like stuttering and aphasia a faster and more natural way to share their thoughts.
Icarus Quantum builds highly efficient photonic hardware that connects standalone quantum computers into powerful, modular networks. This technology solves the major scaling problem in quantum computing by acting as a universal translator that allows different types of quantum systems to communicate and share information seamlessly.
Quantum Logic develops ultra-cold hardware using superconducting circuits to manage and route radio-frequency signals in quantum computers. This technology reduces wiring complexity and prevents overheating, solving a critical bottleneck that currently stops quantum systems from scaling into large, practical machines.
Veloce builds a software and robotics platform that installs automated robot arms into existing commercial kitchens to cook full menus. This helps restaurants solve severe labor shortages and improve low profit margins without having to change their recipes or remodel their spaces.
Whelix builds AI-powered robotic systems that fully automate cell culture experiments, turning digital drug discovery into real-world physical tests. This technology replaces slow, manual lab work with a system that runs around the clock, allowing researchers to speed up the creation of new medicines and produce highly consistent results.
Better Bionics builds affordable, highly dexterous robotic hands with sensory feedback for amputees and humanoid robots. This technology solves the high abandonment rate of current prosthetics while providing the complex manipulation data needed to train general-purpose robots.
Mission Space builds a network of in-orbit sensors and predictive models to provide real-time space weather forecasts for satellite and lunar operators. This intelligence allows companies to protect their spacecraft from radiation, drag, and communication disruptions that cause significant financial damage.
Pollentia builds an embedded AI operating system that acts as a central brain for boats by connecting sensors, navigation, and diagnostics into a single platform. This technology prevents costly vessel failures and brings modern, predictive intelligence to the outdated marine industry.